Where is restylane refyne used?

Restylane Refyne is commonly used to treat nasolabial folds, ranging from the sides of the nose to the corners of the mouth; puppet lines, which extend from the corners of the mouth to the chin) and other wrinkles around the nose and mouth.


Refyne is an injectable filler used to treat moderate to severe “laugh lines” around the mouth. Results last up to 12 months. Restylane Defyne can be used for deeper nasolabial folds, also known as “laugh lines”.

Restylane fillers are made of hyaluronic acid, a natural substance in the skin. Restylane Refyne is an FDA-approved hyaluronic acid filler used for the treatment of smile lines and expression lines. Dynamic wrinkles, such as nasolabial folds, are often the result of a lifetime of laughing, smiling and talking, but genetics can make them look even more deeply. Restylane Refyne is a state-of-the-art dermal filler designed to soften expression lines.

Through Xpreshan technology, Restylane Refyne can help improve your natural look while maintaining facial expressions and movement. Restylane Defyne and Restylane Refyne are the only fillers on the market that have been shown in a clinical study to help maintain movement and expressions. The unique gel crosslink in Restylane Refyne is also designed to help support your natural expression and get real-life results that help maintain natural movement when you smile, frown, and even frown. Restylane Defyne is also used to treat puppet lines, the folds that go from the corners of the mouth to the chin.

The most common and mild side effects after Restylane Refyne include pain during the injection, swelling at the placement site, or bruising. Restylane Defyne is mainly used to treat lines from the nose to the corners of the mouth, known as nasolabial folds. The side effects of Restylane Refyne are similar to any other FDA-approved injectable hyaluronic acid filler product. The FDA approved Restylane Refyne for the treatment of moderate to severe facial wrinkles and folds, along with Restylane Defyne for moderate to severe deep wrinkles and folds.

In addition, due to its filling structure, Restylane Refyne can provide longer wear and allow for less swelling than some previous fillers used to reduce wrinkles. Restylane Refyne uses a hyaluronic gel formation that allows you to contour and shape the filler, offering a personalized and natural look. Subjects were evaluated based on perceived naturalness of moving facial expressions after 1 month of optimal treatment with Restylane Refyne and Restylane Defyne. Refyne is used to correct deeper wrinkles on the face, such as nasolabial folds (smile lines).

While there are other fillers on the market that can fill in wrinkles, Refyne and Defyne are intended to give a more natural-looking result than previously thought possible. Every time you laugh, cry or frown, Refyne and Defyne facial fillers will continue to look soft and natural instead of stiff and puffy. Restylane Defyne is usually ideal for this area due to its advanced XpressHan formulation, which provides greater support and is generally more flexible than conventional hyaluronic acid-based fillers.

Gwendolyn Steckler
Gwendolyn Steckler

Lifelong music nerd. Social media buff. Amateur tv expert. Professional zombie specialist. Award-winning twitteraholic. Wannabe food nerd.